paradox

Paradox and Quantum Mechanics: When Reality Plays by Strange Rules

Human curiosity has always been driven by a desire to understand the universe in simple, logical terms. Yet, sometimes nature answers our questions with a riddle, a contradiction, or what scientists call a paradox. Paradoxes are situations that defy intuition or challenge the way we think reality should behave. They can be thought of as intellectual knots—puzzles that seem to say, “Wait… how can that be true?”

When we step into the world of quantum mechanics—the branch of physics that studies the smallest particles in existence—paradoxes don’t just appear occasionally; they seem to be everywhere. The deeper we look, the more we realize that the universe doesn’t always play by the rules we thought we knew.

What Is a Paradox?

A paradox occurs when two apparently contradictory ideas or facts both seem true at the same time. Some paradoxes are just misunderstandings of language or logic. Others, especially in science, are genuine phenomena where reality behaves in ways that challenge our understanding.

For example:

  • In the grandfather paradox, if you travel back in time and prevent your grandfather from meeting your grandmother, you wouldn’t be born—but if you were never born, how could you travel back to stop them from meeting?
  • In the liar paradox, the statement “This sentence is false” can’t be consistently labeled as true or false.

While these are thought experiments, quantum mechanics introduces real-life situations where paradox-like behavior is measurable and repeatable.

Quantum Mechanics: The Playground of Paradox

quantum mechanics
quantum mechanics

Quantum mechanics deals with the behavior of particles like electrons, photons, and atoms. These particles exist at scales so small that the classical laws of physics—like Newton’s laws—stop working in a predictable way.

Instead, particles in the quantum realm seem to obey strange rules:

  • They can exist in multiple states at the same time (superposition).
  • They can be linked across space instantly (entanglement).
  • They don’t seem to have definite properties until measured (wavefunction collapse).

These behaviors often sound like science fiction, but they’ve been confirmed repeatedly by experiments. The challenge is that they don’t match how we experience the everyday world, which is why so many paradoxes arise.

Famous Quantum Paradoxes

  1. Schrödinger’s Cat

Proposed by physicist Erwin Schrödinger in 1935, this thought experiment involves a cat in a sealed box with a quantum trigger that has a 50% chance of killing it. Quantum theory says that until we open the box and observe the cat, it’s both alive and dead—a superposition of states. This is not a literal suggestion about cats, but a way to highlight the weirdness of applying quantum rules to larger objects.

2. The EPR Paradox

In 1935, Einstein, Podolsky, and Rosen proposed a paradox to challenge quantum mechanics. They argued that if two particles are entangled and separated by vast distances, a measurement on one instantly affects the other—implying “spooky action at a distance.” Einstein thought this meant quantum theory was incomplete. Later experiments confirmed that entanglement is real and instantaneous, even if it defies classical logic.

3. The Quantum Zeno Effect

This paradox says that a quantum system’s evolution can be “frozen” by constantly observing it. In other words, the act of measurement can stop change from happening—something that sounds impossible but has been observed experimentally.

Why Do Quantum Paradoxes Matter?

These paradoxes are more than brain teasers. They are clues that our everyday assumptions about reality may be incomplete. In fact, quantum mechanics has given rise to revolutionary technologies:

  • Quantum computers that can solve problems classical computers can’t.
  • Quantum cryptography for ultra-secure communication.
  • Quantum sensors with precision far beyond current limits.

By wrestling with paradoxes, scientists often discover deeper truths about the universe.

Philosophical Implications

Quantum paradoxes force us to ask fundamental questions:

  • Is reality objective, or does it depend on observation?
  • Do particles exist in a definite state before we look?
  • Is the universe deterministic, or does chance play a fundamental role?

These questions blur the line between physics and philosophy, showing that understanding the universe isn’t just about equations—it’s about rethinking what “reality” means.

Conclusion

Paradoxes in quantum mechanics remind us that nature is under no obligation to conform to human intuition. The universe operates according to its own principles, even if they seem contradictory or strange to us. By exploring these paradoxes, scientists aren’t just solving puzzles—they’re peeling back layers of reality itself.

Quantum mechanics may be full of mystery, but it’s through grappling with these mysteries that we expand the boundaries of human knowledge. And perhaps, in the process, we’ll come to see that the universe’s most puzzling paradox is not how strange it is—but how perfectly it works.

microbiota

Effect of Our Emotions on Gut Microbiota 2025

Abstract

Latest researches in neuroscience and Gut microbiota have uncovered a fascinating connection between our emotions, the hormones in our bodies, and the bacteria living in our guts. This review is an effort to gather scientific explanations on  how our feelings can actually affect the composition of gut microbiota through neurohormones.

Introduction

The human gut gives shalter to trillions of colonies of microorganisms, collectively termed the gut microbiota, which executes essential roles in digestion, metabolism, and immune function. Emerging evidence reveals that emotional experiences—such as stress, anxiety, and positive affect—modulate the composition and function of gut microbiota. Central to this modulation is neurohormonal signaling along the gut-brain axis.

The Gut-Brain Axis: Bidirectional Communication

The gut-brain axis is a two directional communication network integrating the central nervous system (CNS), the enteric nervous system (ENS), the hypothalamic-pituitary-adrenal (HPA) axis, and the gut microbiota. Our feelings and thoughts really do affect how our stomach works and even the types of bacteria living inside our gut. This connection happens through various systems in our body – like the nerves, hormones and also the immune system response. So basically, when we’re in a certain mood or overthinking things, it can actually mess with what’s happening in our gut.

  • Endocrine signaling: Neurohormones released in response to emotions, including cortisol, norepinephrine, and serotonin, influence the gut environment.
  • Immune mechanisms: Stress and emotion-induced immune changes can impact gut permeability and microbial communities

Emotional States and Neurohormonal Signaling Stress and Negative Emotions

Emotional stress triggers activation of the HPA axis, resulting in increased secretion of corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and ultimately cortisol. These stress hormones have widespread effects on gut barrier function, immunity, and microbial homeostasis.

  • Acute and chronic stress can induce rapid shifts in gut microbial composition in both mucosal and luminal compartments[5]. Specific studies in animal models show increased gut permeability, inflammation, and overgrowth of pathogenic bacteria under stress conditions.
  • Neurohormones such as norepinephrine and cortisol directly modulate bacterial growth and virulence. In vitro, catecholamines can significantly increase certain bacterial populations and enhance their pathogenicity.

Positive Emotions

Positive emotions correlate with distinct gut microbiome profiles. Individuals exhibiting positive affect and emotion regulation have lower abundance of inflammation-associated bacteria and higher levels of beneficial taxa. Specific metabolic pathways related to energy, coenzyme A, and neurotransmitter synthesis also differ with emotional states.

Emotion Regulation

Cognitive strategies that regulate emotion—such as reappraisal or suppression—can alter neurohormonal output, indirectly shaping the gut microbial community.

Neurohormones as Mediators

Neurohormones serve as crucial mediators between emotions and gut microbiota. They are produced both by host tissues (e.g., adrenal glands, enteric neurons) and in some cases by gut microbes themselves.

Important Neurohormones

  • Serotonin: Over 90% of the body’s serotonin is synthesized in the gut, with production regulated by both the microbiota and host cells. Changes in serotonin levels affect gut motility and mood.
  • Dopamine: Some gut bacteria (e.g., Bacillus, Serratia) produce dopamine, influencing both gut and brain signals.
  • GABA, norepinephrine, acetylcholine: Microbes modulate and respond to these neurotransmitters, thereby mediating stress-related effects on gut ecology.

The Impact of Emotional Disorders

Several mental and emotional disorders—including anxiety, depression, and chronic stress—have been linked to gut dysbiosis[10][5]. Shifts in bacterial taxa, decreased diversity, and increased inflammation are often observed in affected individuals. Novel interventions using probiotics and psychobiotics are being explored to restore microbial balance and alleviate emotional symptoms.

Mechanistic Insights

  • Barrier Function: Stress and negative emotions compromise intestinal and blood-brain barriers, facilitating bacterial translocation and contributing to systemic inflammation.
  • Microbial Metabolism: Emotional states alter microbial metabolism, impacting energy, vitamin, and neurotransmitter synthesis pathways in the gut.
  • Immune Interactions: Emotional distress promotes immune activation in the gut, further shaping the microbiota and increasing risk of gastrointestinal pathology.

Table: Emotions, Neurohormones, and Gut Microbiota Interactions

Neurohormones
table

Conclusion

Human emotions exert significant effects on gut microbiota through neurohormonal signaling along the gut-brain axis. Stress and negative feelings typically induce dysbiosis, while positive emotional states and effective emotion regulation appear to support a healthier gut microbial landscape. Continued research in this area may hold promise for innovative therapies targeting the microbiome to promote both mental and physical well-being.

Professor Dr. Kartikey

Author Name

Professor Dr. Kartikey

food waste

Peels, Pulps and Potential: The Rise of Upcycled Food 2025

Wasting food is like stealing from the table of those who are poor and hungry.

Every year, India produces an estimated 68 million tonnes of food waste, which is roughly 22% of the total food produced in the nation

At the same time, an alarming percentage of our population faces the grappling issue of malnutrition, hunger or lack of access to food. While the two sides of the same coin gnaw at us, and food continues to fall into landfills, a crucial question arises from the paradox : “Can food waste be reimagined as a resource?”

The answer lies in the quiet revolution reshaping our food industry– Upcycled Food.

What is Upcycled Food?

Upcycled food refers to food made by using ingredients which would otherwise be discarded such as peels, pulp, husk, seeds etc. Unlike leftover or expired food, upcycled food uses by- products from food processing which are at times even more nutritious and perfectly safe to consume. It is the process of transforming them into value added items through innovative processing and cutting down on food wastage.

Need of Upcycled Food

According to FAO, food loss and waste result in the wastage of 30 % of agricultural land, 20 % of freshwater, 38 % of total energy consumption, and contribute to 8 % of human-caused greenhouse gas emissions. Hence, food loss and waste represent significant wastage of water, resources, and land, profoundly impacting climate change. While millions of people go hungry parallely with massive food waste, upcycled food bridges the gap by transforming the by-products (often seen as food waste) into edible products. It supports sustainability, offers affordable nutrition and removes the burden of food waste. It’s not just an innovation but a necessity. 

Upcycled Food in India

Long before the term “upcycled food” entered the global lexicon, Indian kitchens were practicing it instinctively. Whether it was turning banana stems into curry, using leftover rice for next-day dishes, or transforming vegetable peels into chutneys, zero-waste cooking was a cultural norm.
India, like many other traditional food cultures (Korea, Japan, Italy), has always respected the integrity of food — from root to rind.

indian food
indian food

Food Technology meets Innovation
By applying techniques like fermentation, drying, dehydration, food technologists are finding new ways to transform waste into edible products.

Some examples of the same are:

  • Fruit peel powders being used in functional foods.
  • Apple pomace used in extruded chips and bakery items.
  • Upcycled flour from banana peels, coconut husk etc.
  • Protein rich food made from Okara, a by product of soy milk residue.

Challenges and Conclusion

Despite its potential, perception remains a hurdle.

Although promising sustainability, upcycled food meets with obstacles in the global narrative, one of them being the perception of waste being unsafe to consume. However, studies show otherwise. For instance, apple peels contain more fiber and antioxidants than the flesh

Ensuring microbial safety, maintaining nutritional quality, and achieving consumer trust are crucial challenges. Yet, with rigorous standards and innovation, upcycled food is rising as a powerful model of circular economy and climate action.

Food upcycling isn’t just a trend, but a movement towards recognizing the real value of food and saving what we’ve lost through years. As India steps into an era of climate responsibility and sustainable, mindful eating, upcycled food offers a powerful way to nourish the planet and its people. One peel at a time!

peel
peel
Maahi lamba 1

Author Name

Maahi Lamba

food safety

WHY FOODTECHNOLOGY??

Food technology is essential for addressing global challenges related to food quality, safety, nutrition, and sustainability. This field is becoming more important than ever due to rising population demands and the growing awareness around health and environmental impact. This research explores why to choose food technology and what opportunities lie beyond it–ranging from innovations like smart farming to careers in research, product development, and food entrepreneurship. The future of food is not
just about feeding people, but doing it smarter, safer, and more sustainably.

What is Food Technology and Food Science

Food Technology

It is a branch of Engineering that deals with the techniques involved in the production, processing, preservation, packaging, labeling, quality management, and distribution of food products. The field also involves techniques and processes that transform raw materials into food. Extensive research goes behind making food items edible as well as nutritious. Food Technology is a fascinating field that
merges science, engineering, and business to create delicious, nutritious, and safe food products.

food technology
food technology

What is Food Science

Food science can be defined by the application of basic science and engineering to study the fundamental physical, chemical, and biochemical nature of food and the principles of food processing.

Top 5 Reasons to Choose a Career in Food Technology:

  • Job Security – Constant demand for food ensures stable career opportunities.
  • Diverse Work Environment – Wide range of roles across labs, manufacturing, sales, education, etc.
  • Passionate Community – Collaborative and service-oriented industry culture.
  • Salary Opportunities – Competitive pay, with high starting and growth potential.
  • Travel Opportunities – Global industry presence allows for domestic and international travel.

Types of Job Roles in Food Technology:

  • Food Technologist
  • Quality Manager
  • Nutritional Therapist (Nutritionist)
  • Regulatory Affairs Officer
  • Product/Process Development Scientist
  • Technical Brewer
  • Food Blogger/Vlogger
  • Chef

Top Recruiting Companies for Food Technologists:

  • MTR Foods Limited
  • AMUL
  • Dabur India Ltd
  • PepsiCo India Holdings
  • Britannia Industries Ltd
  • Nestle India Pvt. Ltd
  • ITC Limited
  • Agro Tech Foods
  • Parle Products PVT Ltd
  • ITC Limited
  • Cadbury India
  • Hindustan Liver Limited
  • Milk Food
  • MTR
  • Nestle India
  • Godrej Industrial Limited

In Food Technology you come across two choices:

B.Sc Food tech- It is a 3-year course which teaches students about Biochemistry, Biotechnology and Basic Sciences involved in Food Processing/Packing/ Manufacturing.

B.Tech in Food Tech – It is a 4-year course engineering program that trains students in the technical concepts of Food process engineering, Food Analysis, and Regulations, Crop Processing Technology, Plant and Animal Biotechnology

Here is a structured table of Government B.Tech Colleges in Food Technology in India accepting JEE Main, based on the extracted content:

College Name and Course

  • Indian Institute of Technology (IIT), Kharagpur B.Tech in Agricultural and Food Engineering West Bengal
  • National Institute of Technology (NIT), Rourkela B.Tech in Food Process Engineering Sundargarh, Odisha
  • Indian Institute of Food Processing Technology (IIFPT), Thanjavur B.Tech in Food Technology Thanjavur, Tamil Nadu
  • Guru Nanak Dev University (GNDU), Amritsar B.Tech in Food Technology Amritsar, Punjab
  • Shivaji University B.Tech in Food Technology Kolhapur, Maharashtra
  • Bundelkhand University B.Tech in Food Technology Jhansi, Uttar Pradesh
  • Raja Balwant Singh Engineering Technical Campus B.Tech in Food Technology Agra, Uttar Pradesh
  • North Maharashtra University, Institute of Chemical Technology (UICT), Jalgaon B.Tech in Food Technology Jalgaon, Maharashtra
  • Ghani Khan Choudhury Institute of Engineering and Technology (GKCIET), Malda B.Tech in Food Technology Malda, West Bengal
  • Government Engineering College, Vaishali B.Tech in Food Technology Vaishali, Bihar

WHAT AFTER BATCHELOR’S IN FOOD TECHNOLOGY?

Master’s Degree in Food Tech:

  • MSc Food Technology
  • MTech Food Technology
  • MBA Food Technology
  • M.voc Food Technology

Msc Food Technology:

Msc
Msc

MSc Food Technology Career Prospects:

  • Qualified postgraduates in Food Technology can easily get jobs in sectors such as Food Packaging Companies, Food Processing Companies, food manufacturing industries, food research laboratories, etc.
  • Students completing post-graduation in Food Technology can also move forward in laboratory-based careers in clinical or technical roles not involving research.
  • There are a large number of job opportunities for those who want to pursue a career in the field of Food Technology. Students can opt for various jobs such as Production Managers, Food Development Manager, Food Packaging Manager, Food Safety auditors, etc.

The departments/institutions where MSc Food Technology can seek employment are:

  • Agri-Food Processing Industries
  • Academics and Research
  • Food Regulatory and Auditing
  • Food Processing and Dairy Processing Cooperatives
COLLEGEFEE STRUCTUREEXAM MODEADMISSION PROCESSPLACEMENT
Central Food
Technological
Research Institute
(CFTRI), Mysore
Approximately
Rs. 50,000 per
year
Admission typically
through
CFTRI
Entrance
Exam or
through GATE
qualification
followed by
interview
Admission
Process:
Apply online
through
CFTRI
website,
appear for entrance exam
(if applicable),
and undergo
interview.
CFTRI has
strong industry
connections
and offers
placements in
reputed food processing
companies.
National Institute
of Food
Technology
Entrepreneurship
and Management
(NIFTEM),
Sonipat
Approximately
Rs. 1.5 lakh per
year
Admission
through
NIFTEM
Entrance
Exam.
Apply online,
appear for
entrance exam,
and participate
in counseling.
Good
placement
record in food
processing
industry and
agri-business
sector.
University of
Delhi (DU) –
Department of
Food Technology
Lower fees,
typically under
Rs. 20,000 per
year.
Admission through
DUET
(Delhi
University
Entrance
Test) or
merit in
qualifying
exams.
Apply online
through DU
admission
portal, appear
for DUET (if
applicable),
and participate
in counseling
Good
placement
opportunities in
food
processing
companies and
research
organizations.
University of
Mysore –
Department of
Food Science and
Nutrition
Around Rs.
30,000 to Rs.
40,000 per year
Admission
through
university-s
pecific
entrance
exams or
merit in
qualifying
exams.
Apply online
through
university
admission
portal, appear
for entrance
exam (if
applicable),
and participate
in counseling.
Decent
placement
opportunities in
food
processing
companies and
research
institutions
Assam
Agricultural
University, Jorhat
Approximately
Rs. 30,000 per
year
Admission
through
AAU
Entrance
Exam or
university-s
pecific
criteria.
Apply online
or offline as
per university
guidelines,
appear for
entrance exam
(if applicable),
Offers
placements in
food
technology and
related sectors
and participate
in counseling.
Banaras Hindu
University
(BHU), Varanasi
– Institute of
Agricultural
Sciences
Around Rs.
25,000 per year
Admission
through
BHU PET
(Postgraduat
e Entrance
Test) or
GATE
scores for
some
programs
Register and
apply online
for BHU PET,
appear for
entrance exam,
and participate
in counseling
Good
placement
record in food
processing
industries,
research
organizations,
etc.
Guru Nanak Dev
University
(GNDU),
Amritsar
Approximately
Rs. 30,000 per
year
Admission
through
university-s
pecific
entrance
exams or
merit in
qualifying
exams.
Apply online
through
university
admission
portal, appear
for entrance
exam (if
applicable),
and participate
in counseling.
Decent
placement
opportunities in
food
processing and
related sectors.

MTech Food Technology:

Duration2 years
EligibilityA valid score in GATE/TANCET
Admission ProcessMinimum 55% in Graduation
BTech/BE/BSc
Course Fee5,000-2,50,000 INR
Average Salary6,00,000Lac approx
Top RecruitersMTR Foods Limited, PepsiCo India,
Dabur Ltd, Hindustan Unilever, ITc
Ltd, Agro Tech Foods, Nestle India Pvt
Ltd.
Job ProfileFood Technologist, Consultant, Quality
Analyst, Nutritionist, Food Production
Engineer.

The key areas of research for MTech Food Technology students at School of Bio-engineering and Food Technology are Food Processing and Preservation, Food Safety and Quality Control, Food Packaging and Shelf Life, Nutraceutical and Functional Food, Livestock Products, Beverage and Fermentation.

Career Opportunities after MTech Food Technology:

This is a dynamic professional course with inclination towards technological aspects of FMCG industry. Therefore, the career opportunities that await MTech Food Technology students include options like:

  • Food Technologist
  • Biochemist
  • Food Inspector
  • Organic Chemist
  • Lab Technician
  • Production Manager
  • Beverage Technologist
COLLEGEFEE STRUCTUREEXAM MODEPLACEMENTADMISSI ON PROCESS
Indian Institute of
Food Processing
Technology
(IIFPT), Thanjavur
IIFPT
Entrance
Exam or
GATE
Generally good
placement
records with
opportunities in
food processing
industries
Through
GATE
score
followed by
an
interview or
through
IIFPT
Entrance
Exam
NIT Rourkela1-5 LAKHGATE , CCMT
National Institute
of Food
Technology
Entrepreneurship
and Management
(NIFTEM),
Sonipat
JEE Main or GATENIFTEM offers
good placement
opportunities in
food technology
and related
sectors
Admission
based on
JEE Main
or GATE
score,
followed by
counselling
IIT GuwahatiINR 1 LAKHGATE
Institute of
Chemical
Technology (ICT),
Mumbai
GATEICT Mumbai has
a strong
placement cell
with
opportunities in
various
industries
including food
technology
Admission
based on
GATE
score
followed by
an
interview
IIT KharagpurINR 20,000-
INR 1 LAKH
GATE

Mba Food Technology:

Degree Name.MBA in Food Technology
DegreeType Postgraduate
Degree Duration2 years
Entrance ExamsCAT, GMAT, MAT or any other State Entrance Exam
Eligibility CriteriaBachelor’s degree
Average Salary.Rs 3.2 LPA (Food Technologist)
Job ProfilesFood Technologist, Quality Manager, etc

MBA Food Technology is an innovative 2-year, full-time degree program that delivers world-class business education to groom professionals who can become leaders of tomorrow. Special focus areas under this program are management of food processing, storage, transportation, distribution, marketing, sales, and profit and loss calculations.

MBA and MTech

  1. Career Goals: If you are more interested in management roles, business development, or entrepreneurship in the food industry, then pursuing an MBA might be the better option. An MBA will provide you with a broader skill set in areas such as finance, marketing, and strategic management.
  2. Industry Demand: Consider the current demand for professionals with an MBA or M.Tech in the food technology industry. Research the job market to understand which qualification is more valued by employers in the roles you are interested in.
  3. Personal Interests: Think about your own interests and strengths. If you enjoy working with technology, conducting research, and solving technical challenges, then an M.Tech might be more fulfilling. On the other hand, if you are interested in business strategy, leadership, and working in a corporate environment, an MBA could be a better fit.
  4. Networking Opportunities: Both MBA and M.Tech programs offer networking opportunities, but in different spheres. An MBA program will allow you to network with business professionals, while anM.Tech program will connect you with experts in the technical and scientific aspects of food technology.
COLLEGEPROGRAM OFFERSEXAM MODEADMISSION
PROCESS
PLACEMENT
National
Institute of
Agricultural
Extension
Management
(MANAGE),
Hyderabad
Offers PGDM in
Agri-Business
Management
CAT or
MANAGE
Entrance
Exam
CAT score
followed by
GD/PI or
MANAGE
Entrance
Exam
Good
placements in
agri-business
and related
sectors
Indian Institute
of
Management
(IIM)
Ahmedaba
Offers PGPM in
Food and
Agri-Business
Management
CATCAT score
followed by
GD/PI
Strong
placements in
food and
agri-business
sectors
Indian Institute
of
Management
(IIM)
Lucknow
Offers PGPM in
Agribusiness
Management
CAT score
followed by
GD/PI
CATGood
placements in
agribusiness
sectors
Indian Institute
of
Management
(IIM)
Kozhikod
Offers PGPM in
Agriculture and
Food
Management
CATCAT score
followed by
GD/PI
Strong
placements in
agriculture and
food sectors
Institute of
Rural
Management
Anand
(IRMA),
Gujarat
Offers PGDRM
(Post Graduate
Diploma in
Rural
Management)
with a focus on
Agribusiness
CAT or XAT
followed by
IRMA Social
Awareness
Test
(IRMASAT)
Good
placements in
rural
management,
agribusiness,
and related
sectors

After MSC?

  • Approach the companies related to food industries like Mother dairy, Britannia, Parle, Amuletc to be recruited in the Research and development section or in their Quality analysis lab.
  • Pursue higher studies for research scholars, PhD The scope for research in this field is very high. Today almost every other institute is opening, different branch of food technology.
  • Get connected with CSIR labs, IISER labs, IIT labs and ICT labs for internship. Dedicated research is carried out in these institutes where they are in a look out for food technology graduate.
  • Few corporate companies also hire people from life science background. Like a few patenting companies. One can approach them for possible positions
  • Try for research position abroad. Food technology is one of the most valued subject abroad. With little bit of direct effort one can land into great opportunists in countries like New Zealand, Singapore etc.
  • Lastly there are many profound institutes all over India dedicated to food technology. These can provide you with an collaborative study of management and food science. One such is NIFTEM (National institute of food technology and management).

Conclusion:

As the world grapples with the challenges of feeding a growing global population, ensuring that food safety and food quality guidelines are adhered to is becoming a bigger concern every day. The multidisciplinary field of food science-combining biology, chemistry, physics, nutrition, and more-plays a crucial role in addressing these challenges.

With Earth’s population projected to surpass 10 billion by the end of the twenty-first century, better understanding the complex interactions between food, the environment, and human health has never been more important. Food scientists play a pivotal role in developing sustainable and efficient food systems to meet the world’s growing needs.

priya yadav

Author Name

Priya Yadav

OTP

The Silent Threat in Your SMS: How OTP Frauds Are Evolving and How to Stay Safe in India 2025

In India’s rapidly digitizing economy, the One-Time Password (OTP) has become the ubiquitous gatekeeper for our financial transactions, online logins, and personal data. From paying bills via UPI to logging into your net banking or even verifying an e-commerce delivery, the OTP is designed as a crucial layer of security. However, this very reliance has made it a prime target for increasingly sophisticated fraudsters, leading to a surge in OTP-related scams that are emptying bank accounts and compromising personal data across the nation.

The Modus Operandi: How OTP Frauds Unfold

Fraudsters employ a range of deceptive tactics to trick unsuspecting individuals into parting with their OTPs:

Phishing and Smishing Scams

phishing_attack
phishing_attack

This is perhaps the most common method. You receive a fake SMS (smishing) or email (phishing) that perfectly mimics your bank, an e-commerce platform, a government agency (like the Income Tax Department), or even a popular delivery service. The message often creates a sense of urgency – “Your account will be blocked!”, “Your KYC is pending!”, “You’ve won a huge prize!”, or “Your package delivery is stuck.” It then directs you to click on a malicious link that leads to a fake website. This website looks identical to the legitimate one and prompts you to enter your banking credentials and, crucially, the OTP you receive. Once entered, the fraudsters gain immediate access to your accounts.

Fake Customer Support Calls (Vishing)

Scammers impersonate bank executives, telecom service providers, or even government officials. They call you, often with spoofed numbers that appear legitimate, and spin a convincing tale – a “suspicious transaction” on your account, a need to “update your details,” or a “problem with your service.” They then manipulate you into sharing the OTP that conveniently arrives on your phone during the call, claiming it’s for “verification” or to “reverse the fraudulent transaction.”

UPI Collect Request Scams

You might receive a UPI “collect request” on your mobile payment app, which appears to be for receiving money. The scammer might call or message you, saying they are sending you a payment or cashback. However, accepting this request and entering your UPI PIN (which acts as an OTP in this context) actually debits money from your account, rather than crediting it.

SIM Swap Fraud

This is a more complex but devastating attack. Fraudsters trick your mobile service provider into issuing them a duplicate SIM card for your number. Once they activate this new SIM, all your calls, SMS, and crucially, your OTPs, are redirected to their device. This gives them full control to reset passwords for your banking apps, e-wallets, and other online accounts, leading to significant financial losses.

Fake Cashback & Reward Scams

You receive an SMS or call proclaiming you’ve won a lottery, a large cashback, or a lucrative offer. To “claim” the prize, you’re instructed to click a link or provide an OTP, which then gives the fraudsters access to your accounts.

Accidental” OTP Scams

A scammer contacts you, claiming they accidentally sent an OTP to your number and politely requests you to share it with them. This is a classic trick to gain access to their intended victim’s account through the OTP meant for that transaction.

Deepfake and AI-powered Scams (Emerging Threat)

deepfake
deepfake

With advancements in Artificial Intelligence, fraudsters are now using AI-generated voices (voice cloning) and even deepfake videos to impersonate trusted individuals (like a family member in distress) or bank officials. This makes their calls and messages incredibly convincing, making it harder to detect the fraud. They might use this to coerce you into sharing an OTP or clicking on malicious links.

The Alarming Trend and RBI’s Stance

The scale of cyber fraud, including OTP scams, is rapidly increasing in India. In 2024, losses due to cyber fraud were reported to be over ₹22,845 crore, a massive 206% rise from the previous year. The Reserve Bank of India (RBI) has been proactive in issuing guidelines and promoting awareness to combat these threats.

Recently, the RBI directed all Scheduled Commercial Banks, Small Finance Banks, Payments Banks, and Co-operative Banks (effective June 30, 2025) to incorporate the Financial Fraud Risk Indicator (FRI) developed by the Department of Telecommunications (DoT). This system classifies mobile numbers based on their risk of financial fraud (Medium, High, or Very High) using data from cybercrime portals, telecom intelligence, and financial institutions. Banks can then use this information in real-time to decline suspicious transactions, issue alerts, or delay high-risk payments, significantly enhancing customer protection.

Furthermore, existing RBI guidelines emphasize:

Zero or Limited Customer Liability: If you report an unauthorized transaction within three working days, your liability is zero. For delays of 4-7 working days, limited liability applies (up to ₹25,000, depending on account type). Prompt reporting is key.

Faster Redressal: Banks are mandated to resolve fraud complaints within 90 working days and provisionally credit the disputed amount within 10 working days.

Customer-Friendly Notification: Banks must provide easy ways to report fraud, including direct links in SMS/email alerts.

How to Protect Yourself: Your Shield Against OTP Fraud

While banks and regulatory bodies are strengthening their defenses, your vigilance is the strongest barrier against OTP fraud.

NEVER SHARE YOUR OTP: This is the golden rule. No bank, financial institution, government agency, or reputable company will ever ask for your OTP over the phone, SMS, email, or chat. Your OTP is for your eyes only, to authorize a transaction you initiated.

Verify the Source: If you receive a suspicious call or message claiming to be from your bank, hang up immediately. Do not call back on the number provided in the message or by the caller. Instead, use the official customer service number listed on your bank’s website or debit/credit card.

Be Wary of Links: Avoid clicking on suspicious links in SMS or emails. These are often phishing attempts designed to steal your credentials. Type official website URLs directly into your browser.

Do Not Install Unverified Apps: Only download applications from official app stores (Google Play Store, Apple App Store) and always check reviews before installing. Be cautious of apps that ask for excessive permissions.

Enable Transaction Alerts: Set up SMS and email alerts for all your banking transactions. This allows you to quickly identify any unauthorized activity.

Report Suspicious Activity Immediately: If you suspect fraud or notice an unauthorized transaction, contact your bank’s fraud helpline immediately to block your cards/accounts. Also, file a complaint on the National Cyber Crime Reporting Portal (www.cybercrime.gov.in ) or call the helpline 1930.

Secure Your Device: Use strong, unique passwords or biometrics (fingerprint/face ID) for your phone and banking apps. Keep your mobile operating system and apps updated to benefit from the latest security patches.

Educate Yourself and Others: Share this knowledge with your family and friends, especially the elderly, who are often prime targets for these scams.

Be Sceptical of “Too Good to Be True” Offers: If an offer sounds incredibly lucrative or demands immediate action, it’s likely a scam.

In the digital age, convenience comes with responsibility. By understanding the evolving tactics of fraudsters and adopting vigilant habits, we can collectively build a stronger defense against OTP frauds and secure our financial well-being.

child feeding

Infant and young child feeding and Gut microbiota

Recent evidences shows development of gut microbiota during infancy affects several metabolic, immune, and endocrine pathways in humans. An inbalance in gut microbiota diversity or function, also known as dysbiosis, not only affects early child growth and development, but is also related with the development of chronic, non-communicable diseases in later life. Maternal diet in pregnancy, mode of delivery, breastfeeding and timing of introduction of solids food all influences gut microbiota composition. Breastfeeding is the most influential factor on gut microbiome composition. There is difference in population of gut microbiome population of breastfed and formula fed infant. There also are evidences showing breastfed infant being less susceptible to communicable and non communicable diseases as compared to formula fed infants. Child undernutrition is a major public health challenge prevalent in low- and middle-income countries. Undernourished children face adverse health consequences that can be intergenerational. Complementary feeding practices started during 6 months which do not meet the WHO’s guiding principles lacking in quantity, quality of food will lead to undernutrition, restrict growth, child development of the child. First 1000 days of life from conception to 2 years are very crucial for a child’s physical and mental development. Establishment of the gut microbiome during early life is a complex process with lasting implications on an individual’s health. This review will summarize the evidence on how IYCF (Infant young child feeding practices) broadly impacts early life gut microbiome composition and function.

Introduction

Infancy is a critical period for establishment of the gut microbiome, and is known to have a long-term impact on health and risk for disease. Microbial colonization of the gastrointestinal (GI) tract is fundamentally linked to metabolic programming, immunologic maturation, and proper gastrointestinal development. Any disturbances in colonization of gut microbiome may lead to many illness like allergy, asthma, inflammatory bowl disease , Diabetes, obesity ,food allergy and many more illness. The healthy fetus is devoid of microbial organisms, but upon birth our gastrointestinal (GI) tract becomes colonized with a multitude of microbes, gradually developing into a complex microbial community during the first year of life. Human milk plays an important role in the development of the infant’s gut microbiome. Up to 88% of the genera are shared between human milk and the breastfed infant’s stool, supporting direct transmission (1).

In addition to direct transmission of the milk microbial community, breastfed infants receive nutrients, human milk oligosaccharides (HMOs), immune cells, antibodies, and secreted proteins that can further modulate the infant’s gut microbiome.

Maternal diet and microbiome

There is evidence to suggest that maternal diet may play a critical role in shaping the microbiome during pregnancy and in neonates independent of maternal body habitus. Maternal dietary intake during pregnancy is associated with maternal gut, vaginal, and milk microbiome composition . thus neonatal microbiome is influenced by the maternal diet. (3,4) Fruit and vegetable consumption also influences the maternal microbiome. Maternal overweight/obesity status has also been associated with alterations in the infant gut microbiome .Increases in pre-pregnancy body mass index (BMI) have been associated with alterations in the maternal gut microbiome. Studies have shown that pregnant mothers in first trimester who were obese prior to pregnancy were found to have a higher relative abundance of Firmicutes and a lower relative abundance of Proteobacteria compared to their normal body weight counterparts (5).This Firmicutes increase the efficiency of energy extraction and promote the absorption of calories .

pragency gut health
pragency gut health

Breastfeeding and microbiome

Breastfeeding shapes the gut microbiota in early life, both directly by exposure of the neonate to the milk microbiota and indirectly, via maternal milk factors that affect bacterial growth and metabolism such as human milk oligosaccharides, secretory IgA, and anti-microbial factors. There are differences in gut microbiota variety of exclusive breastfed and non breastfed infants. Benefits of breastfeeding   is due to its effect on infant gut micobiota. Beneficial bacteria are transferred from breastmilk and also from skin around mothers areola. The gut microbiome in breastfed infants is usually dominated by bifidobacteria and Lactobacillus species, while formula-fed infants harbor a more diverse gut microbiota that resembles that of older children .The retrograde flow and the entero-mammary pathway are accepted as the two primary source of origin of milk microbiota . In retrograde flow there is transmission of microbes from infants mouth to mammary duct during suckling and in enteromammary pathway there is translocation of maternal gut bacteria through intestinal epithelial barrier to reach mammary gland via lympathic circulation. Several factors can influence the composition of the human milk microbiota (HMM)  maternal age, parity, socioeconomic status, antibiotic use, probiotics during pregnancy and type of delivery. The human milk microbiota is the second integral source of microbes after birth canal and the mammary glands , periareolar skin and the infants mouth can influence its composition. Bifidobacterium and Lactobaccillus has a probiotic role. Few strains of lactobacillus also has antioxidant and anticancer activities. Human milk microbiota can influence infants health in two ways 1) by promoting intestinal immune homeostasis and 2)fascilitating  digestive process. Human milk provide antigenic stimuli that promotes intestinal immune maturation system. Microbes produce SCFA by fermentation of HMO (Human milk oligosaccharides) which has a immunomodulatoy effect on host physiology. Many factors like diet, ethnicity, location, medication can impart variability in milk microbiota. Thus breastfed infant is protected from various bacteria and virus as compared to formulafed infants. There are lower incidences of gastrointestinal infection and upper respiratory inection in breastfed infants. There are lower chances of asthma, diabetes, obesity in these infants as compared to formula fed infants.

Complementary Feeding and Gut microbiome

Complementary feeding period is a period when solid food are first introduced to infants after 6 months of age. Introducing correct food is crucial for infants growth and development. Diversified diet will provide essential micronutrients and will also help growth of diverse gut microbiome. The complementary feeding period offers a unique opportunity to shape the gut microbiome, potentially influencing outcomes like growth trajectories, obesity risk, immune function, and allergic disease development. As complementary feeding progress milk based component is replaced by fruits ,vegetables,  fibres, meat, pulses and cereals which effects growth and development . These food influences gut microbiota ,increases alpha diversity and increases bacteria that produce SCFAs and BCFAs. This “natural” development of the gut microbiota and its metabolites is associated with healthy growth, neuro, bone development, and appropriate immune system regulation.

Processed food can significantly effect gut microbiota. These food have less fibres, preservatives, colours, emulsifier and other chemicals which can cause negative effects. Processed food can decrease diversity and increase harmful bacteria. The ultra processed food high in fats, high in sugars and salt additives and acellular nutrients ,low in vitamins .They weaken the gut barrier, disrupt hormonal regulation, and increase the risk of inflammation and related diseases .Food additives have toxic effect on microbiota and  artificial sweetners are known to be etiological factor to inflammatory bowel disease.

Thus ultraprocessed food causes change in microbiota composition, promoting the growth of inflammatory bacteria associated with conditions such as type 2 diabetes, cardiovascular diseases, and metabolic disorders.

Conclusion

Dysbiosis or imbalance in gut microbiota can be caused by  factors  like maternal diet, maternal obesity, mode of delivery, introduction of formula milk, inappropriate complementary food, introduction of ultraprocessed foods. Dysbiosis is linked with inflammatory bowl diseases, obesity, diabetes ,metabolic syndrome, depression and anxiety. Breastfeeding  and correct complementary food plays a crucial role in protection of all these conditions. Formula fed infants have different gastrointestinal microbiome and health outcomes as compared to breastfed infants.  Children consuming excess ultraprocessed food are also seen suffering from anxiety, depression and other mental issues. This may be related to dysbiosis and its effect on gut brain axis. Introducing probiotics like lactobacillus and bifidobacterium,probiotics like dietary fibres,  synbiotics, postbiotics (SCFA)can have a protective effect against mental disorders by  beneficial gut microbiota  and suppressing harmful ones.

Bina

Author Name

Dr Bina ketan Bharadva

MBBS,IBCLC
Lactation consultant and Infant young child nutrition counselor
Perinatal mental health counselor

beyond_headset_metaverse

Beyond the Headset: How the Metaverse is Reshaping Our Real World

For many, the word “Metaverse” still conjures images of fantastical VR games and futuristic digital playgrounds. While gaming has undoubtedly been a powerful catalyst, the true potential of the Metaverse lies far beyond mere entertainment. We’re now in 2025, and the immersive, interconnected digital realm is quietly, yet profoundly, reshaping how we learn, work, and socialize in the real world.

The Metaverse is evolving into a persistent, shared virtual space where digital avatars represent us, allowing for interactions that feel more akin to physical presence than traditional video calls. This blend of virtual and reality is opening up unprecedented possibilities.

Education Reimagined: Immersive Learning Without Borders

Imagine stepping into a virtual anatomy lab to dissect a 3D human heart, collaborating on a complex engineering problem with students from across the globe in a shared virtual workspace, or taking a historical field trip to ancient Rome – all without leaving your home in Jamshedpur. This is the promise of the Metaverse in education.

Virtual Classrooms and Labs

The days of static textbooks are numbered. Metaverse platforms offer interactive 3D classrooms where students can engage with content, conduct virtual experiments, and participate in simulations. This hands-on, experiential learning significantly boosts comprehension and retention.

Accessible Learning

For students in remote areas or those with physical limitations, the Metaverse breaks down geographical barriers. Quality education, once a privilege, becomes more inclusive and accessible.

Personalized Learning Paths

AI-driven virtual tutors and adaptive learning systems within the Metaverse can tailor educational experiences to individual learning styles and paces, ensuring every student gets the support they need.

Virtual Field Trips and Internships

From exploring the Amazon rainforest to shadowing a surgeon in a virtual operating theatre, the Metaverse provides immersive experiences that would be impossible or impractical in the physical world.

The Future of Work

Collaborative, Immersive, and Global
Remote and hybrid work models are here to stay, and the Metaverse is offering a more engaging evolution of these setups, going beyond flat video conferencing.

Virtual Workplaces and Meeting Rooms

Companies are creating digital twin offices where teams can collaborate as avatars, fostering a sense of presence and team cohesion that traditional video calls often lack. Digital whiteboards, 3D model sharing, and immersive presentations become the norm.

Enhanced Collaboration

Engineers can virtually inspect a new product prototype, architects can walk clients through a future building design, and designers can iterate on concepts in a shared 3D space, all in real-time. This reduces travel, saves costs, and accelerates innovation.

Corporate Training and Onboarding

The Metaverse provides a safe, controlled environment for high-risk training scenarios (e.g., medical procedures, industrial operations) without real-world consequences. New hires can onboard in a virtual office, meeting colleagues and learning company culture in a more engaging way.

Global Talent Pools

With truly immersive virtual workplaces, geographical location becomes less of a constraint, allowing companies to tap into a wider, more diverse talent pool worldwide, including right here in India.

Social Interaction Evolved

Connecting in New Dimensions
Beyond gaming, the social fabric of the Metaverse is weaving new ways for people to connect, share experiences, and build communities.

Immersive Social Platforms

social connection metaverse
social connection metaverse

Unlike 2D social media, the Metaverse allows for interactions through customizable avatars, voice, and even gestures, mimicking real-world social cues more effectively. Think of virtual concerts, art exhibitions, or even just casual meetups that feel more personal and engaging.

Virtual Events and Conferences

The pandemic accelerated the adoption of virtual events, and the Metaverse is taking them to the next level. Conferences, trade shows, product launches, and cultural festivals can host millions globally in detailed, interactive virtual venues, complete with exhibition halls, stages, and networking areas.

Community Building

Niche communities are flourishing in the Metaverse, centered around shared hobbies, interests, or professional networks. These virtual spaces foster deeper connections and a stronger sense of belonging.

Digital Identity and Self-Expression: Avatars allow for unparalleled self-expression and identity exploration, giving users the freedom to present themselves in new and creative ways.

The Road Ahead

While the Metaverse is still in its early stages of development, particularly in terms of seamless interoperability and widespread accessibility, the momentum is undeniable. Here in India, increasing smartphone penetration, the 5G rollout, and a tech-savvy population are key drivers for Metaverse adoption.

Conclusion

As engineers continue to refine immersive technologies, improve network infrastructure, and address critical issues like data privacy and digital ethics, the Metaverse will increasingly become an integral part of our daily lives. It’s not just about escaping reality; it’s about expanding it, offering richer, more connected, and more impactful experiences in education, work, and how we socialize. The future is being built, one pixelated (or hyper-realistic) experience at a time.

Therapeutics

Peptide-Based Cancer Therapeutics: An In Silico Approach to Targeted Drug Discovery

Abstract

Peptide-based therapeutics are emerging as a rapidly expanding and highly promising class of anti-cancer agents, owing to their inherent high target specificity, relatively low toxicity compared to conventional chemotherapeutics, and their versatile design potential. These characteristics make them particularly attractive candidates in the search for novel cancer treatments.

Recent advances in the fields of bioinformatics, computational biology, and structural biology have revolutionized the strategies employed to identify, model, and screen these peptides. These technologies enable high-throughput, data-driven approaches to the discovery and optimization of peptide drugs, vastly accelerating the traditional drug development process.

This article proposes a comprehensive computational pipeline designed to facilitate the identification and rational design of anticancer peptides derived from natural toxins—potent molecules that have evolved to interact precisely with biological targets. By leveraging detailed structural and molecular modeling, the pipeline focuses on elucidating the interactions between these candidate peptides and cancer-specific receptors at the atomic level. This approach not only highlights their potential therapeutic value but also enhances our understanding of the mechanisms underlying peptide-receptor binding and selectivity.

Ultimately, this framework lays the groundwork for a data-driven peptide drug discovery process that can be iteratively refined and expanded as new computational tools and experimental data become available. By integrating computational prediction with experimental validation, researchers can accelerate the translation of these promising peptides from in silico models to preclinical and clinical applications, thus contributing to the advancement of precision oncology.

Intruduction

The search for targeted and less toxic anticancer drugs has led researchers to increasingly revisit nature’s vast pharmacopoeia, recognizing it as a rich reservoir of bioactive compounds with therapeutic potential. Among the most compelling emerging candidates in this domain are bioactive peptides derived from natural toxins, including those found in leech venom. These peptides exhibit highly specific interactions with molecular targets implicated in tumorigenesis, offering unique and often underexplored mechanisms of action that can disrupt critical cancer pathways while sparing healthy tissues.

Computational Pipeline for Peptide Drug Discovery

  1. Peptide Design and Sequence Optimization

Peptides were selected based on known anti-thrombotic and anti-proliferative motifs in Hirudin (a leech-derived peptide). Sequence optimization was performed using anti-cancer peptide prediction servers (e.g., iACP, CancerPPD) to enhance cytotoxic potential while minimizing immunogenicity.

The integration of sophisticated bioinformatics tools and high-throughput screening platforms into this discovery process has dramatically accelerated the early stages of peptide drug development. By combining sequence analysis, molecular modeling, and in silico docking studies, researchers can rapidly identify, optimize, and prioritize candidate peptides for further experimental validation. This computational approach not only reduces the time and cost associated with traditional wet-lab screening but also enhances the precision and rationality of peptide design, paving the way for the development of novel anticancer therapeutics with improved efficacy and safety profiles.

2. Structure Prediction

3D models of the peptides were generated using PEP-FOLD3 and validated via
Ramachandran plot analysis to ensure stereochemical stability.

3. Target Selection and Preparation

Receptor proteins such as AXL and EGFR, implicated in aggressive cancer phenotypes, were
retrieved from the Protein Data Bank. These receptors play a critical role in tumor
progression and resistance to existing therapies.

4. Molecular Docking

Molecular Docking
Molecular Docking

Docking simulations were conducted using HADDOCK and AutoDock Vina. Key parameters
analyzed included binding affinity, hydrogen bonding, and interface residues. Peptides
exhibiting strong interaction with the receptor binding sites were shortlisted for further
validation.

5. In Silico Toxicity and Stability Profiling

ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) analysis was performed using tools like SwissADME and ToxinPred. Candidates with favorable pharmacokinetic profiles and non-toxic predictions were prioritized.

6. Results and Discussion

Several peptides showed nanomolar binding affinity toward AXL and EGFR, suggesting potential therapeutic efficacy. Molecular interaction analysis revealed key residues contributing to stable peptide-receptor complexes. The docking scores correlated with known anti-tumor peptide characteristics, highlighting the power of computational screening in identifying viable therapeutic leads.

Additionally, in silico toxicity prediction allowed early-stage elimination of peptides with
poor safety profiles, saving significant time and resources in downstream experimental
validation.

Conclusion and Future Prospects

This study highlights the potential of computational pipelines in peptide drug discovery, particularly in the context of cancer therapy. With the increasing availability of biological data and AI-driven prediction models, bioinformatics is poised to become an indispensable tool in next-generation precision oncology.

Further experimental validation and in vitro studies will be critical to translating these computational findings into clinical breakthroughs

Varshini Arun

Author Name

VARSHINI ARUN